Colorectal Cancer

Colorectal cancer is a common malignant tumor, including colon cancer and rectal cancer. The occurrence of colorectal cancer is related to a high-fat and low-fiber diet, chronic bowel diseases, genetics and other factors. The age of onset tends to be older, and it often occurs in middle-aged and elderly people over 40 years old, with a male-to-female ratio of 1.65:1. In the later stage of colorectal cancer, symptoms such as changes in defecate characteristics, hematic defecate, and abdominal pain will occur. Early diagnosis and timely surgery are the keys to the diagnosis and treatment of colorectal cancer.

Diagnosis of Colorectal Cancer

Laboratory examinations for colorectal cancer:

• Fecal occult blood test. It is the main method for screening colorectal cancer.
• Tumor marker examination. Carcinoembryonic antigen (CEA) and CA19-9 are important tumor markers that need to be detected in patients with colorectal cancer. These two tumor markers can assess the disease and detect recurrence.
• Immunohistochemistry and genetic monitoring. It is recommended to detect the expression of mismatch repair proteins (MLH1, MSH2, MSH6, PMS2), tumor Kras, N-ras, BRAF gene status, mismatch repair defects (dMMR) and tumor microsatellite instability (MSI), which can guide the medication of colorectal cancer patients.

Laboratory tests can be used to understand whether the patient has iron deficiency anemia and the basic conditions of liver and kidney function, which is helpful for the diagnosis of tumors and is a preliminary diagnosis method for colon cancer. In addition to laboratory tests, the diagnosis of colorectal cancer also includes colonoscopy, biopsy and imaging diagnosis.

Advantages of Our Products

Creative Biogene's colorectal cancer diagnostic products include a series of diagnostic kits, and its analysis modes are lateral flow, immunochemical, enzyme immunoassay and latex agglutination, etc. Our products can be used for adenomatous polyp screening, early detection of gastrointestinal diseases, as well as collecting and testing specimens for signs of occult blood, which are early signs of colorectal cancer. The advantages of our diagnostic products are:

• Standardized kits make the operation process quick and easy.
• High accuracy, sensitivity, specificity and reproducibility.
• No need to control diet before the test.

Creative Biogene has accumulated years of experience in colorectal cancer diagnosis. We promise to provide you with the best diagnostic products. You can choose us with confidence.

Please contact us for more details.

Reference

1. Hu Z, et al. (2019). "Quantitative evidence for early metastatic seeding in colorectal cancer." Nature Genetics 51.7: 1113.