Bacterial Vaginitis

Bacterial vaginitis (BV) is a mixed infection of Gardnerella vaginalis and some anaerobic bacteria, which leads to the imbalance of the microecological balance in the vagina, resulting in increased vaginal secretions, leucorrhea with a fishy smell, and genital pruritus burning syndrome. Bacterial vaginitis can be divided into Haemophilus vaginitis, Corynebacterium vaginitis, anaerobic vaginitis, Gardnerella vaginitis and so on. The disease is transmitted through sexual contact and has a higher incidence in people with promiscuous sexual relations. Bacterial vaginosis is considered to be the most common cause of vaginal inflammation in women. European and American research report shows a prevalence between 4.9% and 36.0%. Oral or topical use of anti-anaerobe drugs is used to treat the disease.

Diagnosis of Bacterial Vaginitis

Vaginal secretions smear test. Take a small number of vaginal secretions and apply it on a glass slide, mix it with saline, and then look for special cells called clue cells under a high-power microscope. If the number of nematode cells accounted for more than 20% of squamous epithelial cells under the microscope, bacterial vaginitis can be diagnosed.

Amine test. Spread a little vaginal secretions on a glass slide and add a few drops of potassium hydroxide solution. If it produces a fishy smell, it indicates bacterial vaginosis.

Vaginal pH test. Test the pH of the vagina. The pH in the normal vagina is mostly 3.8-4.4, and the vaginal pH of patients with bacterial vaginosis is generally greater than 4.5, but this method is not specific.

PCR detection. The RT-PCR method was used to detect Gardnerella vaginalis, Ectopic vaginalis, Lactobacillus, and the total number of bacteria in the vaginal biological community.

DNA probe test. Compared with other diagnostic methods, detecting the genetic components of pathogenic bacteria can provide more objective test results.

Advantages of Our Products

Creative Biogene's test kit adopts real-time PCR method to quantitatively or qualitatively detect vaginal microorganisms to achieve the purpose of diagnosing bacterial vaginitis, and also to check the treatment effect. Our kits have excellent performance in detection speed, sensitivity, accuracy and specificity.

Creative Biogene's skilled scientists have extensive experience in developing diagnostic products for bacterial vaginitis. It is sincerely looking forward to cooperating with you and providing you the best quality product with all our hearts! You can choose us without hesitation.

Please contact us for more details.

Reference

1. VanD P, et al. (2019). "Molecular-based testing for sexually transmitted infections using samples previously collected for vaginitis diagnosis." Clinical Infectious Diseases. 68.3: 375-381.