Varicella

Chickenpox is an acute infectious disease caused by the varicella-zoster virus, which can cause symptoms such as systemic macules, papules, herpes, and scabs. This disease is more common in children, and will naturally stop or self-healing at a certain stage. The disease is extremely contagious and can be spread through droplets through the respiratory tract or direct contact with the local mucosa after entering the body and multiplying, but it does not have infectiousness after scabs. Most patients can form antibodies in the body after recovery, and no longer be infected with varicella, but the latent virus in the body later activated can cause shingles. Immune insufficiency, newborns, pregnant women, and long-term oral corticosteroids are high-risk groups of varicella virus infection. If a pregnant woman suffers from varicella, her fetus may be infected and cause deformities.

Diagnosis of Varicella

There are several ways to test varicella:

• Electron microscopy. Take fresh herpes fluid for electron microscopy. Herpes virus particles can be seen, which can be quickly distinguished from variola virus.
• Routine blood test. The total number of white blood cells is normal or increased, and the percentage of lymphocytes may be increased.
• Serological test. The most commonly used test is the complement fixation test. Complement fixation antibodies appear in the serum of patients with varicella 1-4 days after the eruption. Fluorescent antibody method can also be used for detection.
• PCR method. The detection of viral DNA in nasopharynx secretions is a sensitive and rapid method of early diagnosis.
• Herpes scrape or tissue biopsy. Fresh varicella is scraped, and examined by Gimsa staining for multinucleated giant cells and by acid staining for inclusions.

Advantages of Our Products

Creative Biogene's test kit uses PCR-fluorescent probe method to quantitatively detect varicella-zoster virus. Our products have the advantages of high sensitivity, strong specificity, speed and simplicity, as well as high throughput, providing accurate and reliable results for your related research.

Creative Bioarray focuses on the research and development of varicella diagnostic products. After years of unremitting efforts, we have become experts in the diagnostic field. We are committed to providing customers with the best products to help you quickly solve the problems in diagnostic research. We look forward to working with you for your cooperation.

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Reference

1. Leung J, et al. (2010). "Evaluation of laboratory methods for diagnosis of varicella." Clinical infectious diseases. 51.1: 23-32.