Hashimoto's Disease

Hashimoto's disease, also known as chronic lymphocytic thyroiditis, is a chronic autoimmune disease with thyroid tissue as antigen. It is the most common thyroid inflammation in the clinic, and more common in middle-aged women, and the prevalence age is 40 to 50 years old. The most typical clinical manifestations of Hashimoto's disease are symptoms related to goiter and hypothyroidism. Hashimoto's disease occurs because the immune system produces autoantibodies that attack the thyroid. Some thyroid follicular cells are destroyed, resulting in insufficient thyroid hormone secretion. In order to maintain the normal function of the body, the undamaged thyroid follicular cells compensate for proliferation to produce more thyroid hormone. When the thyroid loses its compensatory ability and appears hypothyroidism, it indicates that 90% of the thyroid follicles have been destroyed.

Diagnosis of Hashimoto's Disease

The diagnosis of Hashimoto's disease depends on the patient's physical signs and symptoms, as well as blood test results. The specific detection methods include:

• Physical examination. If you have symptoms such as fatigue, dullness, dry skin, constipation, hoarseness, and goiter, you need further examination for Hashimoto's disease.
• Blood test. With the progression of the disease, thyroid-stimulating hormone (TSH) increases, and FT3 and FT4 are still in the normal range. After entering the thyroid function decline period, FT3 and FT4 both decreased, and TSH increased.
• Antibody test. Serum thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb) titers increased significantly, which are the most meaningful diagnostic indicators.
• Thyroid fine-needle puncture cytology. The examination is less traumatic, and can show medium or large lymphocyte infiltration pathologically.
• Imaging diagnosis. Including thyroid ultrasonography, thyroid radionuclide imaging and so on.

Advantages of Our Products

Creative Biogene's test kits use enzyme-linked immunosorbent assay (ELISA) to qualitatively or semi-qualitatively detect anti-thyroglobulin or thyroid peroxidase autoantibodies in human serum for the diagnosis of Hashimoto's disease. Our products have the advantages of high accuracy, strong specificity, reliable technology, easy operation, etc., which can help you to complete the related research more smoothly.

Creative Bioarray has a professional team of experts who developed quality Hashimoto's disease diagnostic products. Our products are competitive in the market due to their reasonable price and high quality, which can help you solve the diagnosis problem quickly. We look forward to working with you for your cooperation.

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Reference

1. Zhang L, et al. (2012). "The clinical features of papillary thyroid cancer in Hashimoto's thyroiditis patients from an area with a high prevalence of Hashimoto's disease." BMC Cancer. 12.1: 610.