Tuberculosis

Tuberculosis is a chronic respiratory infectious disease caused by Mycobacterium tuberculosis. The lesions mainly occur in lung tissue, trachea, bronchus as well as pleura, and pulmonary tuberculosis infection is the most common. Tuberculosis can be divided into three categories: latent infection of Mycobacterium tuberculosis, active tuberculosis and inactive tuberculosis. Human infection with Mycobacterium tuberculosis is the basic cause of tuberculosis. Healthy people may be infected when they inhale droplets of Mycobacterium tuberculosis, and there is a possibility of further developing into pulmonary tuberculosis. Whether the onset of disease also depends on factors such as human immunity, the number and virulence of Mycobacterium tuberculosis. If the infected person can be diagnosed in time and given reasonable treatment, most of them will get clinical recovery.

Diagnosis of Tuberculosis

Tuberculosis can be diagnosed by:

• Chest imaging examination. Chest X-ray is the first choice for the diagnosis of tuberculosis. It can detect early mild tuberculosis lesions, determine the extent, location, shape and density of the lesion. Then to determine whether the lesion is active, whether there is cavitation, etc. CT can improve the resolution, evaluate the subtle features of the lesions, and assist to find hidden chest and trachea, intrabronchial lesions easily. It is usually used for the diagnosis of tuberculosis and the differential diagnosis of other chest diseases.
• Bacteriological examination. The specimens are sputum, body fluids and pus, etc. Mycobacterium tuberculosis examination is the main method for diagnosing tuberculosis, and also the main basis for formulating chemotherapy plan and evaluating the therapeutic effect. The Mycobacterium culture of the patient is positive, and the strain is identified as Mycobacterium tuberculosis complex.
• Molecular biology examination. A positive nucleic acid test for Mycobacterium tuberculosis indicates the infection of the bacterium.
• Pathological examination. Including puncture smear examination, biopsy pathological diagnosis.
• Immunological examination. Tuberculin skin test, γ-interferon release test, and the Mycobacterium tuberculosis antibody are positive, which can also help determine whether it is Mycobacterium tuberculosis infection.
• Bronchoscopy. Bronchial mucosal hyperemia, ulcers, erosions, tissue hyperplasia, and bronchial stenosis can be observed.

Advantages of Our Products

Creative Biogene's tuberculosis detection kits are mostly based on immunochromatography or real-time PCR to detect and identify the pathogen Mycobacterium tuberculosis. The biochemical, immunological and molecular biological properties of Mycobacterium tuberculosis have allowed people to identify several antigens, which will help to improve the diagnostic methods to distinguish Mycobacterium tuberculosis complexes from tuberculosis branches other than Mycobacterium tuberculosis Bacillus. Our products have fast detection speed, high sensitivity, reproducibility and accuracy.

Creative Biogene focuses on the field of diagnostic reagents for tuberculosis. We are committed to providing the best products to accelerate the realization of customers' research goals.

Please contact us for more details.

Reference

1. Talaat R M, et al. (2010). "Rapid immunodiagnostic assays for Mycobacterium Tuberculosis infection." Health. 2.3:171-176.