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Syphilis

SyphillisSyphilis is a chronic and systemic sexually transmitted disease caused by Treponema pallidum (TP) infection. It is mainly transmitted through sexual contact, mother-to-child transmission and blood transmission. It can be clinically manifested as primary syphilis, secondary syphilis. , Tertiary syphilis, latent syphilis and congenital syphilis, etc. The disease is extremely harmful, and the lesion can affect almost all tissues and organs of the human body. Syphilis during pregnancy can also cause premature delivery, abortion, stillbirth and neonatal syphilis. Syphilis is prevalent all over the world. According to WHO estimates, there are about 12 million new cases each year in the world, mainly in South Asia, Southeast Asia and Sub-Saharan Africa.

Diagnosis of Syphilis

There are several ways to test for syphilis:

Dark field microscopy. Take skin ulcer exudate or lymph node puncture fluid, test under a dark field microscope, and see the movable Treponema pallidum, which can be used as the basis for the diagnosis of syphilis. But the detection rate is low.

Syphilis serological test. By testing the blood for the presence of Treponema pallidum-related antibodies, including specific antibodies and non-specific antibodies. Antibodies from the bacteria that cause syphilis will remain in the body for many years, so this test can be used to determine current or past infections.

Cerebrospinal fluid examination. It is mainly used for the diagnosis of neurosyphilis. This test is helpful for the diagnosis, treatment, and prognosis of neurosyphilis. The examination items should include cell count, total protein determination, RPR and TPPA tests, etc.

Advantages of Our Products

Creative Biogene's test kits mostly use methods such as ELISA or latex agglutination to detect the presence of syphilis-related antibodies in serum samples to help diagnose the disease. Using our products can get accurate test results quickly to ensure the efficiency of your research. In addition, the price and after-sales service of our products are also very competitive in the market.

Creative Biogene's skilled scientists have extensive experience in developing diagnostic products for syphilis. It is sincerely looking forward to cooperating with you and providing you the best quality product with all our hearts! You can choose us without hesitation.

Please contact us for more details.

Reference

  1. Morshed M G and Ameeta E S. (2015). "Recent trends in the serologic diagnosis of syphilis." Clinical and vaccine immunology: CVI. 22.2: 137.
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