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Typhoid

TyphoidTyphoid fever is an acute intestinal infectious disease caused by Salmonella typhi. Typical symptoms include persistent high fever, abdominal pain, hepatomegaly, and low white blood cells. Some patients have rose rash and relatively slow pulse. In severe cases, indifference and slow reaction may occur. Typhoid fever carriers and patients are the only source of infection. The disease is mainly transmitted through the fecal-oral route, contaminated water and food can cause outbreaks.

Diagnosis of Typhoid

Typhoid can be detected by the following methods:

  • Blood routine. The number of white blood cells decreased, the proportion of lymphocytes increased relatively, and eosinophils decreased or disappeared.
  • Serum agglutination test. The titers of antibodies corresponding to Salmonella typhi bacteria antigen O and flagella antigen H in the patient's serum can be determined. If the above-mentioned antibody titers increase by more than 4 times during the recovery period, it can assist in the diagnosis of typhoid fever.
  • Salmonella typhi culture. Positive blood and bone marrow cultures have diagnostic significance, and the positive rate of bone marrow culture is higher than that of blood culture. A positive stool culture can also confirm the diagnosis.
  • Pathological examination. Roseola shows telangiectasia and mononuclear cell infiltration under the microscope, and sometimes typhoid bacilli can be seen.

Advantages of Our Products

Creative Biogene's test kit is a rapid test for the qualitative detection of Salmonella typhi IgM and IgG antibodies in human whole blood, serum or plasma. Compared with other traditional detection methods, our Salmonella typhi detection kit is a simple and fast laboratory detection product, which has excellent performance in sensitivity, specificity and accuracy.

Creative Biogene focuses on the research and development of typhoid diagnostic products. After years of unremitting efforts, we have become experts in the diagnostic field. We are committed to providing customers with the best products to help you quickly solve the problems in diagnostic research. We look forward to working with you for your cooperation.

Please contact us for more details.

Reference

  1. Adhikari A, et al. (2015). "Evaluation of sensitivity and specificity of ELISA against Widal test for typhoid diagnosis in endemic population of Kathmandu." BMC infectious diseases. 15.1: 1-7.
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