Oncology

Cancer is a time bomb that grows in the human body. It develops rapidly and becomes very difficult to treat once it deteriorates. It seriously endangers human health and life. The best way to treat cancer is early diagnosis. About 80%-90% of early cancer patients can be cured. In order not to miss the best time to treat cancer, a comprehensive cancer screening is extremely important. The molecular diagnosis of a tumor is one of the key links in the early diagnosis of cancer.

Tumor molecular diagnosis refers to the molecular biological diagnosis technology with nucleic acid or protein as the core. Through the detection of biomacromolecules related to tumorigenesis, the prediction and diagnosis of tumorigenesis can be carried out, and the effect of tumor treatment can be evaluated, which can provide references for the prognosis and outcome of tumors.

Diagnosis Object

• Tumor-related genes. The tumor-related genes include proto-oncogenes (cellular oncogenes) and tumor suppressor genes. Common proto-oncogene families include src family, ras family, myc family, sis family and myb family, etc. The common tumor suppressor genes are Rb gene and P53 gene.
• Tumor-related virus genes. The tumor-related virus is a type of animal virus that can make sensitive hosts produce tumors or transform cells cultured in vitro into cancer cells, including DNA viruses and RNA viruses. Tumor-causing DNA viruses include HPV, HBV, EBV, HHV-8, etc., and tumor-causing RNA viruses include HTLV-1, HCV, etc.
• Tumor markers. Tumor markers refer to substances produced by malignant tumors or by tumor-stimulating host cells, which can reflect the occurrence, development and anti-tumor therapeutic response of malignant tumors. Its expression level in cells or changes in body fluid content is closely related to the occurrence, development and transformation of tumors. Tumor markers that have been discovered so far include embryonic proteins, glycoproteins, enzymes and isoenzymes, hormones, special proteins, and oncogene proteins.

Diagnosis Method

• Genetic testing. Gene testing includes in situ hybridization, fluorescence in situ hybridization, in situ PCR, Southern hybridization, Northern hybridization, comparative genomic hybridization and so on.
• Tumor markers detection. The detection methods of tumor markers are immunohistochemistry, enzyme-linked immunosorbent assay, Western blotting technology, flow cytometry, protein chip, tissue chip, radioimmunoassay, immunoelectron microscopy, apoptotic cell detection and biological mass spectrometry, etc.

Diagnosis Products of Oncology

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