TORCH Infections

TORCH is the acronym for a group of pathogenic microorganisms, with T for toxoplasma, O for other pathogenic microorganisms, such as Treponema pallidum, herpes zoster virus, parvovirus B19, Coxsackie virus, etc., and R for rubella virus, C for cytomegalovirus and H for herpes virus. Most TORCH-infected mothers have no clinical symptoms, but they are potentially harmful to the fetus and newborn. Microbes can cause intrauterine infections through the placenta or birth canal, causing miscarriage, stillbirth, intrauterine growth retardation or malformations, and neonatal congenital infections. TORCH infection is one of the important factors that seriously endanger the health of newborns. Therefore, the TORCH test for pregnant women or newborns has important practical significance to the prenatal and postnatal care.

Diagnosis of TORCH Infections

There are several methods to detect TORCH infection:

• Enzyme-linked immunoassay. The most convenient and commonly used early screening method is ELISA. ELISA methods can detect specific IgM and IgG antibodies in human serum. Because IgM is an indicator of early infection and has a huge impact on the fetus, the detection of IgM has attracted much attention. The detection of specific IgM in the placenta is a reliable basis for diagnosing intrauterine infections in the fetus. ELISA reagents are widely used in ordinary laboratories because of their stability, high sensitivity, strong specificity, and low cost. However, they are generally used for qualitative, not quantitative.
• Chemiluminescence. The chemiluminescence method is used for quantitative detection. The methodology evaluation shows that the sensitivity of CLIA determination is high, the variation within and between batches is small, and it has good anti-interference ability, which can remove the possible interference of virus IgG antibody and rheumatoid factor in the sample, and is suitable for routine clinical work.

Advantages of Our Products

Creative Biogene's TORCH infections test kits use enzyme-linked immunoassay to detect specific IgM and IgG in the serum of TORCH infected patients, contributing to clinical and laboratory diagnosis and research of this disease. Our products have the advantages of sensitivity, high accuracy, good reproducibility and simple operation.

Creative Biogene focuses on the research and development of TORCH infections diagnostic products. After years of unremitting efforts, we have become experts in the diagnostic field. We are committed to providing customers with the best products to help you quickly solve the problems in diagnostic research. We look forward to working with you for your cooperation.

Please contact us for more details.

Reference

1. Yadav R, et al. (2014). "A review on TORCH: groups of congenital infection during pregnancy." J Sci In Res. 3.2: 258-264.