Rubella

Rubella is an acute respiratory infection caused by the rubella virus (RV), including congenital infection and acquired infection. The clinical manifestations are symptoms of upper respiratory tract infection such as cough, sore throat, fever, etc. After 1-2 days of fever, a rash begins to appear, accompanied by cervical lymphadenopathy. Generally, the condition is mild, the course of the disease is short, and the prognosis is good. However, rubella is very easy to cause outbreaks of infection, which can occur all year round, and the susceptible age is mainly 1-5 years old. After a pregnant woman is infected with rubella virus in the early stage, although the clinical symptoms are mild, the virus can infect the fetus through the fetal blood barrier, leading to congenital rubella syndrome (CRS), which is dominated by infant congenital defects, such as congenital fetal malformations, stillbirth, and premature delivery, etc. Therefore, early diagnosis and prevention of rubella are extremely important. There is currently no specific treatment for rubella, but immunization can prevent the disease.

Diagnosis of Rubella

There are several ways to diagnose rubella:

• Physical examination. The patient has a skin rash and conjunctival congestion. Lymph nodes in the neck are swollen and may be tender.
• Blood routine test. The total number of leukocytes decreases, the proportion of lymphocytes increases, and atypical lymphocytes may appear.
• Virological examination. Virus isolation was performed on throat swabs from 4-5 days before the rash to 1-2 days after the rash, and the detection rate is high.
• Serological examination. Serum rubella hemagglutination inhibitor antibodies were tested in the acute and recovery phases and they are positive. The rubella IgM antibody was positive for 5-14 days after the onset of the rash, and the rubella lgG antibody and the lgM antibody appeared almost simultaneously and continued to rise. If the antibody titer in the recovery phase is 4 times or higher than that in the acute phase, it may indicate a recent rubella infection.

Advantages of Our Products

Creative Biogene's rubella test kits adopt a variety of methods to detect antibodies in the serum. The detection methods include ELISA, lateral flow, LIA immunoassay and so on. Our products have high sensitivity, specificity and accuracy, and fast test speed, which can greatly improve the efficiency of your related research, and are your best choice.

Creative Biogene's skilled scientists have extensive experience in developing diagnostic products for rubella. It is sincerely looking forward to cooperating with you and providing you the best quality product with all of our hearts! You can choose us without hesitation.

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Reference

1. Vaheri A and Salonen E. M. (2010). "Evaluation of solid-phase enzyme-immunoassay procedure in immunity surveys and diagnosis of rubella." Journal of Medical Virology. 5.3:171-181.