Dry Eye Disease

Dry eye disease, also known as dysfunctional tear syndrome, is a common eye condition. Due to insufficient tear secretion or excessive evaporation, the number of tears, the quality of tears, and the natural fluidity of tears are abnormal, which will cause tear film instability and/or ocular surface damage, resulting in eye discomfort symptoms and visual dysfunction. Patients often experience eye fatigue, foreign body sensation, dryness and other symptoms, such a type of disease is called dry eye. Recent studies believe that changes in the ocular surface, immune-based inflammation, apoptosis, and changes in sex hormone levels are related factors for the development of dry eye disease, and the relationship between the factors is not yet clear.

Diagnosis of Dry Eye Disease

The lack of correlation between the clinical signs and symptoms of dry eye disease makes diagnosing and treating patients a challenge. In many cases, inflammation is present before the clinical symptoms of dry eye appear. Dry eye cannot be diagnosed by any single test, it needs to be combined with medical history and multiple diagnostic tests for comprehensive analysis. Commonly used dry eye diagnostic tests include the following:

Tear break-up time. If the tear film break-up time is less than 10 seconds, the tear film is unstable, and subsequent steps should be performed. This test is suitable for preliminary screening of dry eye.

Tear osmotic pressure test. The osmotic pressure of tears in patients with dry eye disease is higher than that of normal people. If the osmotic pressure is greater than 312 mOsm/L, dry eye disease can be diagnosed. The test has high specificity and is helpful for early diagnosis.

Inflammation marker detection. MMP-9 protein continues to rise in the tears of patients with dry eye disease, which can be used as a verification marker of the disease. Detecting the content of MMP-9 in tears can be used not only for diagnosis, but also for observing curative effects.

Advantages of Our Products

Creative Biogene's test kits quantitatively measure MMP-9 protein in human tears immunoassay methods, and they are designed to help patients with dry eye disease and other conditions. Our products are simple and convenient to operate, can quickly obtain accurate detection results, and have high sensitivity and specificity. It is the best choice for your related research.

Creative Biogene focuses on the research and development of dry eye disease diagnostic products. After years of unremitting efforts, we have become experts in the diagnostic field. We are committed to providing customers with the best products to help you quickly solve the problems in diagnostic research. We look forward to working with you for your cooperation.

Please contact us for more details.

Reference

1. Messmer E M. (2015). "The pathophysiology, diagnosis, and treatment of dry eye disease." Deutsches Ärzteblatt International. 112.5: 71.