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| Catalog: | C0042A |
| Product Type: | Antibody |
| Reactivity: | H |
| Analysis mode: | IHC |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 0.75 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% Proclin300, 50% glycerol, pH7.3 |
| Purification method: | Antigen affinity purification |
| Application: | Signal Transduction, Stem Cells |
| Conjugation: | Unconjugated |
| Immunogen: | TGFBR2 |
| Swiss port: | P37173 |
| Genn_ID: | 7048 |
| Celluar localization: | Cell membrane, Membrane |
| Tissue specificity: | Cytoplasm, Cytoskeleton, Membrane, Mitochondrion, Nucleus |
Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis.
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