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TGFB2 polyclonal antibody

  • Product Information
  • Description
Catalog: C0167A
Product Type: Antibody
Reactivity: H,M,R
Analysis mode: WB,IHC
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 0.95 mg/mL
Storage: -20℃
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.3
Purification method: Antigen affinity purification
Application: Signal Transduction, Stem Cells, Cancer, Metabolism
Conjugation: Unconjugated
Immunogen: TGFB2
Swiss port: P61812
Genn_ID: 7042
Celluar localization: Extracellular matrix, Secreted

This gene encodes a member of the transforming growth factor β (TGFB) cytokine family, a multifunctional peptide that regulates proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing signals through transmembrane receptors type I and II Type combination (TGFBR1 and TGFBR2) and its downstream effector, SMAD protein. Disruption of the TGFB/SMAD pathway is associated with a variety of human cancers. The encoded protein secretes and inhibits the growth of interleukin-2 dependent t cells. The t(1, 7)(q41, p21) shift between this gene and HDAC9 is related to Peters abnormality, which is a congenital defect of the anterior chamber of the eye. Knockout mice lacking this gene show perinatal mortality and a series of developmental defects, including heart defects.

Verification Code

Diagnostic Development

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