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| Catalog: | C0640A |
| Product Type: | Antibody |
| Reactivity: | H,M,R |
| Analysis mode: | IHC,ELISA |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 0.4 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification method: | Affinity purification |
| Application: | Cancer, Signal Transduction |
| Conjugation: | Unconjugated |
| Immunogen: | TAX1BP1 |
| Swiss port: | Q86VP1 |
| Gene accession: | BC050358 |
| Celluar localization: | Cytosol, extracellular region or secreted, extracellular exosome |
This gene encodes HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits tnf-induced apoptosis by mediating the anti-apoptotic activity of TNFAIP3. The degradation of caspase-3 like family proteins is related to TNF-induced apoptosis. The protein may also play a role in inhibiting inflammation signaling pathways. Another splice transcription variant encoding a different isoform has been found for this gene.
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