Catalog: | C0033A |
Product Type: | Antibody |
Reactivity: | M,R |
Analysis mode: | IHC |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 0.96mg/mL |
Storage: | -20℃ |
Buffer: | PBS with 0.05% Proclin300 and 50% glycerol, pH7.3 |
Purification method: | Antigen affinity purification |
Application: | Signal Transduction, Cancer, Cell Biology |
Conjugation: | Unconjugated |
Immunogen: | ST14 |
Swiss port: | P56677 |
Genn_ID: | 19143 |
Celluar localization: | Membrane |
Tissue specificity: | Degrade the extracellular matrix. Play a certain role in the invasion and metastasis of breast cancer. |
The protein encoded by this gene is an intact membrane serine protease derived from epithelium. The protease forms a complex with the Kunitz-type serine protease inhibitor HAI-1 and was found to be activated by sphingosine 1-phosphate. The protease has been shown to cleave and activate hepatocyte growth factor/scattering factor and urokinase plasminogen activator, indicating that the protease acts as an epithelial membrane to activate other proteases and potential growth factors.
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