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| Catalog: | C0576A |
| Product Type: | Antibody |
| Reactivity: | H,M,R |
| Analysis mode: | WB,IHC |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% Proclin300, 50% glycerol, pH7.3 |
| Purification method: | Antigen Affinity Purification |
| Application: | Immunology, Cell Biology |
| Conjugation: | Unconjugated |
| Immunogen: | SERPINB2 |
| Swiss port: | P12388 |
| Genn_ID: | 18788 |
| Celluar localization: | Cytoplasm, Secreted |
Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor that can inactivate tPA and urokinase. It is present in most cells, especially monocytes/macrophages. PAI-2 exists in an extracellular glycosylated form of 60 kda and an intracellular glycosylated form of 43 kda. Since it is produced by the placenta, it is only present in a detectable amount in the blood during pregnancy, which may partly explain the increase in thrombosis rate during pregnancy.
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