S100A9 human, sheep polyclonal antibody

S100A9 is a calcium binding protein, which was originally discovered in a variety of inflammatory reactions. S100A9 is located in bone marrow cells, cancer cells and tumor stroma. S100A8 and S100A9 are the lowest expression in normal esophageal epithelial cells, but S100A9 is expressed in Barrett's esophagus through adenocarcinoma. S100A8 and S100A9 belong to a family of 25 homologous low-molecular-weight intracellular calcium binding proteins with tissue and cell-specific expression. These proteins are associated with chronic inflammatory diseases such as rheumatoid arthritis (RA), cystic fibrosis, Crohns disease, ulcerative colitis, allergic dermatitis and infections.