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| Catalog: | C0005A |
| Product Type: | Antibody |
| Reactivity: | H |
| Analysis mode: | IHC |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 0.36 mg/mL |
| Storage: | -20°C |
| Buffer: | PBS with 0.05% Proclin300 and 50% glycerol, pH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Neuroscience |
| Conjugation: | Unconjugated |
| Immunogen: | S100A8 |
| Swiss port: | P05109 |
| Genn_ID: | 6279 |
| Celluar localization: | Secreted, Nucleus, Cell membrane, Cytoplasm |
| Tissue specificity: | Expressed in chronic inflammations and epithelial cells constitutively, or induced during dermatoses. |
S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. This protein may function in the inhibition of casein kinase and as a cytokine, and altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
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