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| Catalog: | C-FC-3968A |
| Product Type: | FCM Antibody |
| Size: | 25 Tests/100 Tests |
| Concentration: | 5 μl/Test, 0.1 mg/ml |
| Reactivity: | Human |
| Specificity: | Human DcR1/TRAILR3 |
| Analysis mode: | FCM |
| Host: | Rabbit |
| Clonality: | Monoclonal |
| Isotype: | IgG |
| Alternate names: | tumor necrosis factor receptor superfamily member 10c |
| Form: | Liquid |
| Shipping: | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage: | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Purification method: | Protein A |
| Conjugation: | APC |
| Immunogen: | Recombinant Human TRAILR3/TNFRSF10C Protein |
| Buffer: | Aqueous solution containing 0.5% BSA and 0.09% sodium azide |
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC.
Core Diagnostic Capabilities
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