USA: 
Europe: 
Email: 
Consultation
| Catalog: | C-FC-3596A |
| Product Type: | FCM Antibody |
| Size: | 25 Tests/100 Tests |
| Concentration: | 10 μl/Test, 0.1 mg/ml |
| Reactivity: | Mouse |
| Specificity: | Mouse 4-1BBL/TNFSF9 |
| Analysis mode: | FCM |
| Host: | Rabbit |
| Clonality: | Monoclonal |
| Isotype: | IgG |
| Alternate names: | tumor necrosis factor (ligand) superfamily, member 9 |
| Form: | Liquid |
| Shipping: | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage: | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Purification method: | Protein A |
| Conjugation: | PE |
| Immunogen: | Recombinant Mouse 4-1BBL / CD137L / TNFSF9 protein |
| Buffer: | Aqueous solution containing 0.5% BSA and 0.1% sodium azide |
| Application: | Cancer Drug Targets |
4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Core Diagnostic Capabilities
Follow Us -
Copyright © 2025 Creative Biogene. All rights reserved.
