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Purified Anti-Mouse/Human CD11b Antibody

  • Product Information
  • Description
Catalog: C-FC-2775A
Product Type: FCM Antibody
Size: 50 μg/100 μg
Reactivity: Mouse/Human
Analysis mode: FCM,IHC,IP
Host: Rat
Isotype: Rat IgG2b, κ
Alternate names: Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Swiss port: P05555,P11215
Clone NO.: M1/70
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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