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Purified Anti-Mouse CD38 Antibody

  • Product Information
  • Description
Catalog: C-FC-2745A
Product Type: FCM Antibody
Size: 25 μg/100 μg
Reactivity: Mouse
Analysis mode: FCM,IHC
Host: Rat
Isotype: Rat IgG2a, κ
Alternate names: ADP-ribosyl cyclase 1,ADPRC 1,CD38,NIM-R5 antigen,2'-phospho-cyclic-ADP-ribose transferase
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Swiss port: P56528
Clone NO.: NIMR5
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

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