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| Catalog: | C-FC-2734A |
| Product Type: | FCM Antibody |
| Size: | 50 μg/100 μg |
| Reactivity: | Mouse |
| Analysis mode: | FCM,IHC,IP |
| Host: | Armenian Hamster |
| Isotype: | Armenian Hamster IgG |
| Alternate names: | CD209 antigen-like protein B,Cd209b,DC-SIGN-related protein 1,DC-SIGNR1,OtB7,CD209,Cd209b |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | Unconjugated |
| Buffer: | PBS with 0.05% Proclin300 |
| Swiss port: | Q8CJ91 |
| Clone NO.: | 22D1 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.
Core Diagnostic Capabilities
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