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Purified Anti-Mouse CD117 Antibody

  • Product Information
  • Description
Catalog: C-FC-2720A
Product Type: FCM Antibody
Size: 50 μg/100 μg
Reactivity: Mouse
Analysis mode: FCM, IHC, IF,IP
Host: Rat
Isotype: Rat IgG2b, κ
Alternate names: Mast/stem cell growth factor receptor Kit,Kit,SCFR,Proto-oncogene c-Kit,Tyrosine-protein kinase Kit,CD117
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Swiss port: P05532
Clone NO.: 2B8
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

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