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Purified Anti-Human/Mouse/Rat CD47 Antibody

  • Product Information
  • Description
Catalog: C-FC-2716A
Product Type: FCM Antibody
Size: 50 μg/100 μg
Reactivity: Human/Mouse/Rat
Analysis mode: FCM
Host: Mouse
Isotype: Mouse IgG1, κ
Alternate names: Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Swiss port: Q08722,Q61735,P97829
Clone NO.: MIAP410
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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