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Purified Anti-Human/Monkey CD154 Antibody

  • Product Information
  • Description
Catalog: C-FC-2714A
Product Type: FCM Antibody
Size: 25 μg/100 μg
Reactivity: Human/Monkey
Analysis mode: FCM, IP
Host: Mouse
Isotype: Mouse IgG2a, κ
Alternate names: CD40L, gp39, TRAP, T-BAM, TNFSF5
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Swiss port: P29965
Clone NO.: 5C8
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

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