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| Catalog: | C-FC-2714A |
| Product Type: | FCM Antibody |
| Size: | 25 μg/100 μg |
| Reactivity: | Human/Monkey |
| Analysis mode: | FCM, IP |
| Host: | Mouse |
| Isotype: | Mouse IgG2a, κ |
| Alternate names: | CD40L, gp39, TRAP, T-BAM, TNFSF5 |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | Unconjugated |
| Buffer: | PBS with 0.05% Proclin300 |
| Swiss port: | P29965 |
| Clone NO.: | 5C8 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.
Core Diagnostic Capabilities
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