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| Catalog: | C-FC-2704A |
| Product Type: | FCM Antibody |
| Size: | 25 μg/100 μg |
| Reactivity: | Human |
| Analysis mode: | FCM,IHC |
| Host: | Mouse |
| Isotype: | Mouse IgG1, κ |
| Alternate names: | Fc fragment of IgG high affinity Ia/b/c receptor,CD64A/B/C,CD64,Fc gamma RI,FCGR1A/B/C,IGFR 1 |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | Unconjugated |
| Buffer: | PBS with 0.05% Proclin300 |
| Swiss port: | A6NKC4,P12314,Q92637 |
| Clone NO.: | 10.1 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
Core Diagnostic Capabilities
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