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Purified Anti-Human CD57 Antibody

  • Product Information
  • Description
Catalog: C-FC-2701A
Product Type: FCM Antibody
Size: 25 μg/100 μg
Reactivity: Human
Analysis mode: FCM,WB,IHC
Host: Mouse
Isotype: Mouse IgM, κ
Alternate names: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,B3GAT1,GlcAT-P,GlcUAT-P,GLCATP
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Swiss port: Q9P2W7
Clone NO.: HNK-1
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).

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