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Purified Anti-Human CD4 Antibody

  • Product Information
  • Description
Catalog: C-FC-2697A
Product Type: FCM Antibody
Size: 25 μg/100 μg
Reactivity: Human
Analysis mode: FCM,IHC,IF
Host: Mouse
Isotype: Mouse IgG1, κ
Alternate names: T-cell surface glycoprotein CD4,CD4,T-cell surface antigen T4/Leu-3,CD4
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Swiss port: P01730
Clone NO.: RPA-T4
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).

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