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| Catalog: | C0003A |
| Product Type: | Antibody |
| Reactivity: | H, M, R |
| Analysis mode: | WB, IHC, IF |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 0.89 mg/mL |
| Storage: | -20°C |
| Buffer: | PBS with 0.05% Proclin300 and 50% glycerol, pH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction |
| Conjugation: | Unconjugated |
| Immunogen: | PTEN |
| Swiss port: | P60484 |
| Genn_ID: | 5728 |
| Celluar localization: | Secreted, Nucleus |
| Tissue specificity: | Expressed at a relatively high level in all adult tissues. |
PTEN products of tumor suppressor genes, are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors, such as brain, breast, kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt.
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