Procalcitonin human, rabbit polyclonal antibody

Procalcitonin (PCT) is the precursor of the hormone calcitonin, which undergoes continuous division in the neuroendocrine cells of the thyroid to form three different molecules: calcitonin; katacalcin and the n-terminal are called aminoprocalcitonin Vegetarian. The level of procalcitonin in the blood of healthy people is low. When the procalcitonin value exceeds 0.25 ng/mL, there is a risk of local bacterial infection. When the procalcitonin value exceeds 0.5 ng/mL, there is a risk of systemic bacterial infection. In serum, the half-life of procalcitonin is between 25 and 30 hours. A study showed that liver cells produce large amounts of procalcitonin after TNF-TNF- and IL-6 stimulation. In acute pancreatitis, procalcitonin is closely related to the occurrence of pancreatic infection. Since procalcitonin has been reported to be elevated in different non-septic diseases (such as severe trauma, acute respiratory distress syndrome, post-transplant rejection, cardiogenic shock, severe burns and heat stroke), it is In the patient category, the ability to identify procalcitonin may be hindered. Compared with IL-2, IL-6, IL-8, CRP and TNF-inhibitors, procalcitonin has the greatest sensitivity and specificity in distinguishing SIRS patients from sepsis patients. Procalcitonin is considered to be one of the earliest and most specific markers of sepsis.