USA:

Europe:

Email:

Consultation

POSTN polyclonal antibody

  • Product Information
  • Description
Catalog: C0135A
Product Type: Antibody
Reactivity: H
Analysis mode: IHC,IF
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 0.79 mg/mL
Storage: -20℃
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4
Purification method: Antigen affinity purification
Application: Cancer, Cardiovascular, Signal Transduction, Tags and Cell Markers
Conjugation: Unconjugated
Immunogen: POSTN
Swiss port: Q15063
Genn_ID: 10631
Celluar localization: Secreted, extracellular matrix, Golgi apparatus
Tissue specificity: Widely expressed with Highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Overexpressed in breast cancers.

POSTN is a 90 kda secreted protein and is now classified as a mother cell protein. It exists in various normal adult tissues and fetal tissues, and plays a role in the development and function of bones, teeth and heart. Studies have shown that in many types of human cancers, including lung, ovarian, breast, and colon cancer, periglobulin is overexpressed. Recent evidence shows that in the normal tissues and stroma of the primary tumor, fibroblasts express pericylobin, which is an essential substance for maintaining cancer stem cells.

Verification Code

Diagnostic Development

top