PNN polyclonal antibody

Pinin is a desmosome-related protein involved in maintaining adhesion between epithelial cells. Pinin is a widespread protein that plays an important role in cell adhesion through its interaction with nuclear complexes. Pinin also participates in pre-mRNA splicing by interacting with the c-terminal RS domain of Moca-type nucleophilin G. Pinin becomes the nucleus in the early stages of embryonic development and maintains this state throughout the developmental period. Pinin deficiency or deficiency can be fatal during the perinatal period and can lead to defects in the heart outflow tract, axial skeleton, upper jaw, and dorsal dermis.