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| Catalog: | C0004A |
| Product Type: | Antibody |
| Reactivity: | H, R |
| Analysis mode: | IHC |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/mL |
| Storage: | -20°C |
| Buffer: | PBS with 0.05% Proclin300 and 50% glycerol, pH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Immunology, Signal Transduction |
| Conjugation: | Unconjugated |
| Immunogen: | PI 3 kinase p110 alpha |
| Swiss port: | P42336 |
| Genn_ID: | 5290 |
| Celluar localization: | Cytoplasm, Cell membrane |
| Tissue specificity: | Highest expression level in adrenal tissue. |
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4, 5)P2. This gene has been found to be oncogenic.
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