Catalog: | C-FC-2216A |
Product Type: | FCM Antibody |
Size: | 20 tests/50 tests/100 tests/500 tests |
Reactivity: | Mouse |
Analysis mode: | FCM |
Host: | Rat |
Isotype: | Rat IgG1, κ |
Alternate names: | Itga2b,GPalpha Iib,CD41,GPIIb |
Form: | Liquid |
Shipping: | Biological ice pack at 4℃ |
Storage: | 2-8℃ |
Conjugation: | PE/Cyanine7 |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Swiss port: | Q9QUM0 |
Clone NO.: | MWReg30 |
Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.
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