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| Catalog: | C-FC-2209A |
| Product Type: | FCM Antibody |
| Size: | 25 μg/50 μg/100 μg/200 μg |
| Reactivity: | Mouse |
| Analysis mode: | FCM |
| Host: | Rat |
| Isotype: | Rat IgG2a, κ |
| Alternate names: | ADP-ribosyl cyclase 1,ADPRC 1,CD38,NIM-R5 antigen，2'-phospho-cyclic-ADP-ribose transferase |
| Form: | Liquid |
| Shipping: | Biological ice pack at 4℃ |
| Storage: | 2-8℃ |
| Conjugation: | PE/Cyanine7 |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Swiss port: | P56528 |
| Clone NO.: | NIMR5 |
| Recommended use: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results or refer to the dilution we used in the experiment. |
CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
Core Diagnostic Capabilities
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