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PE/Cyanine5 Anti-Rat CD45 Antibody

  • Product Information
  • Description
Catalog: C-FC-1861A
Product Type: FCM Antibody
Size: 20 tests/50 tests/100 tests/500 tests
Reactivity: Rat
Analysis mode: FCM
Host: Mouse
Isotype: Mouse IgG1, κ
Alternate names: Receptor-type tyrosine-protein phosphatase C,Leukocyte common antigen, LCA, T200, Ly-5,Ptprc
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: PE/Cyanine5
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: P04157
Clone NO.: OX-1
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

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