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PE/Cyanine5 Anti-Human CD57 Antibody

  • Product Information
  • Description
Catalog: C-FC-1737A
Product Type: FCM Antibody
Size: 20 tests/50 tests/100 tests/200 tests
Reactivity: Human
Analysis mode: FCM
Host: Mouse
Isotype: Mouse IgM, κ
Alternate names: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,B3GAT1,GlcAT-P,GlcUAT-P,GLCATP
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: PE/Cyanine5
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: Q9P2W7
Clone NO.: HNK-1
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).

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