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PE Anti-Mouse CD40 (1C10)

  • Product Information
  • Description
Catalog: C-FC-4860A
Product Type: FCM Antibody
Size: 0.1 mg/ml
Reactivity: Mouse
Positive FC: BALB/c mouse splenocytes
Recommended dilution: This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Analysis mode: FC
Host: Rat
Isotype: IgG2a
Alternate names: AI326936, Bp50, Cd40, CD40 antigen, GP39, HIGM1, IGM, IMD3, p50, T BAM, Tnfrsf5, TRAP
Storage: 2-8°C
Purification method: Affinity purification
Immunogen: sCD40
Genn_ID: 21939
Gene accession: BC029254
Gene symbol: Cd40
Buffer: PBS with 0.1% sodium azide and a stabilizer.

CD40, also named as TNFRSF5 and Bp50, is a type I transmembrane protein that belongs to the tumor necrosis factor-R (TNF-R) family (PMID: 10647992). CD40 is expressed on B cells, dendritic cells (DCs), monocytes, platelets, and macrophages as well as by non-hematopoietic cells such as myofibroblasts, fibroblasts, epithelial, and endothelial cells (PMID: 19426221). It is a receptor for TNFSF5/CD40LG. CD40L/CD40 interactions are essential for immunoglobulin (Ig) isotype switching, germinal center formation and the development of B cell memory (PMID: 7516405; 11675497).

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