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PE Anti-Mouse CD366/Tim-3 Antibody

  • Product Information
  • Description
Catalog: C-FC-1564A
Product Type: FCM Antibody
Size: 20 tests/50 tests/100 tests/200 tests
Reactivity: Mouse
Analysis mode: FCM
Host: Rat
Isotype: Rat IgG2a, κ
Alternate names: TIM3, TIMD3,HAVcr-2,TIMD-3
Form: Liquid
Shipping: Biological ice pack at 4℃
Storage: 2-8℃
Conjugation: PE
Buffer: PBS with 0.05% Proclin300, 1% BSA
Swiss port: Q8TDQ0
Clone NO.: RMT3-23
Recommended use: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

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