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| Catalog: | C-FC-4821A |
| Product Type: | FCM Antibody |
| Size: | 20 µl/test |
| Reactivity: | Human, Non-human primates |
| Positive FC: | human peripheral blood platelets |
| Recommended dilution: | This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 4 µl per 10^6 cells in a 100 µl suspension or 4 µl per 100 µl of whole blood. |
| Analysis mode: | FC |
| Host: | Mouse |
| Isotype: | Mouse IgG1 kappa |
| Alternate names: | CD62, CD62P, FLJ45155, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, SELP |
| Storage: | 2-8°C |
| Purification method: | The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
| Immunogen: | Human platelets |
| Genn_ID: | 6403 |
| Gene accession: | BC028067 |
| Gene symbol: | SELP |
| Buffer: | PBS with 0.1% sodium azide. |
P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
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