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| Catalog: | C-FC-4773A |
| Product Type: | FCM Antibody |
| Size: | 10 µl/test |
| Reactivity: | Human |
| Positive FC: | HUVEC cells |
| Recommended dilution: | This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 10 µl per 10^6 cells in a 100 µl suspension or 10 µl per 100 µl of whole blood. |
| Analysis mode: | FC |
| Host: | Mouse |
| Isotype: | IgG1 |
| Alternate names: | CD106, DKFZp779G2333, INCAM 100, L1CAM, V CAM 1, VCAM 1, VCAM1 |
| Storage: | 2-8°C |
| Purification method: | Affinity purification |
| Immunogen: | N/A |
| Genn_ID: | 7412 |
| Gene accession: | BC017276 |
| Gene symbol: | VCAM1 |
| Buffer: | PBS with 0.1% sodium azide and a stabilizer. |
Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843).
Core Diagnostic Capabilities
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