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| Catalog: | C0022A |
| Product Type: | Antibody |
| Reactivity: | H,M,R |
| Analysis mode: | WB,IHC |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 0.33 mg/mL |
| Storage: | -20°C |
| Buffer: | PBS with 0.05% Proclin300 and 50% glycerol, pH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Cell Biology, Epigenetics, Nuclear Signaling |
| Conjugation: | Unconjugated |
| Immunogen: | PDCD4 |
| Swiss port: | Q53EL6 |
| Genn_ID: | 27250 |
| Celluar localization: | Cytoplasm, Nucleus |
Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation, progression and invasion. It was initially identified as upregulation in varying degrees during apoptosis. Pdcd4 interferes with the activity of eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A.
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