PBX1 polyclonal antibody

PBX1, also known as pre-b cell leukemia transcription factor 1, is a 430 amino acid protein belonging to the TALE/PBX homeobox family. PBX1 is expressed in all tissues except B and T cells. The complex of PBX1 and MEIS1 acts as a transcriptional activator of PF4. PBX1 may play a role in steroid production and subsequent sexual development and differentiation. The PBX1b subtype in pancreatic acinar cells is involved in the transcriptional activation of ELA1 enhancer as part of the PDX1:PBX1b:MEIS2b complex. There are two subtypes of PBX1, PBX1a and PBX1b. The molecular weight of PBX1 is 47 kDa and 38 kDa, respectively.