USA:

Europe:

Email:

Consultation

P16-INK4A polyclonal antibody

  • Product Information
  • Description
Catalog: C0535A
Product Type: Antibody
Analysis mode: WB, IP, FC, CoIP, ELISA
Species specificity: Human, monkey
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 370 μg/mL
Storage: -20℃
Buffer: PBS with 0.1% sodium azide and 50% glycerol pH 7.3
Purification method: Antigen affinity purification
Conjugation: Unconjugated
Immunogen: CDKN2A
Genn_ID: 1029
Gene accession: BC021998

CDKN2A produces several transcript variants that differ in their first exon. At least three alternative splicing variants encoding different proteins have been reported. Among them, p16-INK4 and p14 share 50% of the identity. The third-p14 (ARF) is completely irrelevant. 10883-1-AP reacts specifically with p16. P16 plays a vital role in regulating the cell cycle. Mutations in P16 increase the risk of various cancers, including melanoma.

Verification Code

Diagnostic Development

top