Catalog: | C0535A |
Product Type: | Antibody |
Analysis mode: | WB, IP, FC, CoIP, ELISA |
Species specificity: | Human, monkey |
Host: | Rabbit |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 370 μg/mL |
Storage: | -20℃ |
Buffer: | PBS with 0.1% sodium azide and 50% glycerol pH 7.3 |
Purification method: | Antigen affinity purification |
Conjugation: | Unconjugated |
Immunogen: | CDKN2A |
Genn_ID: | 1029 |
Gene accession: | BC021998 |
CDKN2A produces several transcript variants that differ in their first exon. At least three alternative splicing variants encoding different proteins have been reported. Among them, p16-INK4 and p14 share 50% of the identity. The third-p14 (ARF) is completely irrelevant. 10883-1-AP reacts specifically with p16. P16 plays a vital role in regulating the cell cycle. Mutations in P16 increase the risk of various cancers, including melanoma.
Copyright © 2024 Creative Biogene. All rights reserved.