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| Catalog: | C0535A |
| Product Type: | Antibody |
| Analysis mode: | WB, IP, FC, CoIP, ELISA |
| Species specificity: | Human, monkey |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 370 μg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.1% sodium azide and 50% glycerol pH 7.3 |
| Purification method: | Antigen affinity purification |
| Conjugation: | Unconjugated |
| Immunogen: | CDKN2A |
| Genn_ID: | 1029 |
| Gene accession: | BC021998 |
CDKN2A produces several transcript variants that differ in their first exon. At least three alternative splicing variants encoding different proteins have been reported. Among them, p16-INK4 and p14 share 50% of the identity. The third-p14 (ARF) is completely irrelevant. 10883-1-AP reacts specifically with p16. P16 plays a vital role in regulating the cell cycle. Mutations in P16 increase the risk of various cancers, including melanoma.
Diagnostic Development
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