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NSMCE3 polyclonal antibody

  • Product Information
  • Description
Catalog: C0464A
Product Type: Antibody
Reactivity: H,M
Analysis mode: WB,IHC,ELISA
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1.4 mg/mL
Storage: -20℃
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Antigen affinity purification
Application: Cancer, Immunology
Conjugation: Unconjugated
Immunogen: NDNL2
Swiss port: Q96MG7
Gene accession: NP619649
Celluar localization: Cytoplasmic and Nuclear
Tissue specificity: Ubiquitous.

The protein encoded by this gene is part of the SMC5-6 chromatin recombination complex and a member of the MAGE superfamily. This is an intron-free gene. A component of the SMC5-SMC6 complex, a complex involved in repairing DNA double-strand breaks through homologous recombination. By recruiting the SMC1-SMC3 internal polyprotein complex to double-strand breaks, the complex may promote homologous recombination of sister chromatids. This complex maintains telomeres through ALT (alternative telomere extension) cell line reorganization and mediates the threonylation of the mask protein complex (telomere) component, which is thought to shelterin complex disassembly in ALT-associated PML bodies (APBs).

Verification Code

Diagnostic Development

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