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| Catalog: | C0463A |
| Product Type: | Antibody |
| Reactivity: | H,M |
| Analysis mode: | WB,IHC,ELISA |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 0.3 mg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification method: | Antigen affinity purification |
| Application: | Cancer, Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation: | Unconjugated |
| Immunogen: | NCK1 |
| Swiss port: | P16333 |
| Gene accession: | BC006403 |
| Celluar localization: | Cytoplasm， Endoplasmic reticulum， Nucleus |
The melanoma Nck protein encoded by this gene is one of the signal transduction proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in signal transduction from receptor tyrosine kinases to downstream signal receptors such as RAS. In addition, splice transcription variants encoding different subtypes have also been discovered.
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