MxA protein human ELISA kit

The MxA protein plays an important role in the cellular antiviral activity of a variety of viruses, including influenza, parainfluenza, measles, Coxsackie, hepatitis B virus and Thogoto virus. The virus is inhibited by the MxA protein in the early stage of its life cycle, shortly after the host cell enters and before the genome is amplified. Human MxA protein accumulates in the cytoplasm and endoplasmic reticulum. The membrane compartment of the intracellular reticulum seems to provide a platform for interaction to facilitate virus target recognition. MxA seems to detect viral infections by sensing and capturing nucleocapsid-like structures. Therefore, the viral components cannot produce new viral particles. In clinical diagnosis, because the basic concentration of MxA protein is very low and its half-life is long, as a marker of viral infection, MxA protein may be more advantageous than other induced proteins. The expression of MxA protein in peripheral blood mononuclear cells may be used as a marker to distinguish between viral diseases and bacterial diseases, and as a reliable marker for the viability of type I IFN in the treatment of chronic viral hepatitis and multiple sclerosis.