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MUC5AC polyclonal antibody

  • Product Information
  • Description
Catalog: C0001A
Product Type: Antibody
Reactivity: H
Analysis mode: IHC
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/mL
Storage: -20℃
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4
Purification method: Antigen affinity purification
Application: Cancer, Immunology, Signal Transduction
Conjugation: Unconjugated
Immunogen: MUC5AC
Swiss port: P98088
Genn_ID: 4586
Celluar localization: Secreted, Cytoplasmic and cell surface
Tissue specificity: It is highly expressed in the mucosal cells and gastric epithelium of respiratory tract surface and overexpressed in many cancers. Barrett's esophageal epithelium and proximal duodenum are also present.

Mucin-5AC is a protein encoded by the human MUC5AC gene. This gene is associated with excessive secretion of mucus in the lung bundles and is associated with chronic obstructive pulmonary disease (COPD). The glycoproteins of the respiratory epithelium of the stomach and respirators form a gel that binds to the inhaled microorganisms and particles to protect the mucous membrane from infection and chemical damage. These microorganisms and particles are then cleared by the mucous sac system. It is highly expressed in mucosal cells on the surface of the respiratory tract, gastric epithelium and many cancers.

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Diagnostic Development

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