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| Catalog: | C0521A |
| Product Type: | Antibody |
| Analysis mode: | IHC, ELISA |
| Species specificity: | Human |
| Host: | Mouse |
| Clonality: | Monoclonal |
| Isotype: | IgG2a |
| Concentration: | 2000 μg/mL |
| Storage: | -20℃ |
| Buffer: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 |
| Purification method: | Antigen affinity purification |
| Conjugation: | Unconjugated |
| Immunogen: | MLANA |
| Genn_ID: | 2315 |
| Gene accession: | BC014423 |
Melan-A is a melanocyte differentiation antigen that can be recognized by autologous cytotoxic T lymphocytes. The Melan-A/MART-1 gene encodes this protein, 20-22 kDa, which is related to the endoplasmic reticulum and melanosomes. The function of this protein is unclear. Melanin-a is isolated as a melanoma-specific antigen. It is a transmembrane protein that is expressed in skin, retina and most cultured melanocytes and melanomas. Melan A is expressed in more than 85% of melanomas.
Diagnostic Development
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